Use Mystic Bids to Forecast Business Growth Now

Lohfeld Consulting’s list of Mystic Bids provides a forward-looking view of significant opportunities the federal government is likely to release over the next two years. The Mystic Bids blog complements our ongoing series—Mega Bids, which highlights active opportunities valued at more than $500M; Mighty Bids, ranging from $10M to $499M; and Mini Bids of less than $10M. We define “active opportunities” as those where the government has already conducted market research, hosted an industry day, or otherwise engaged with potential offerors. By contrast, Mystic Bids shines a light on forecasted procurements still in development, giving contractors an early look at where the market is heading. In this edition, we highlight 12 major opportunities valued in the billions, ranging from pharmaceutical distribution to cyber defense, next-generation IT infrastructure, and environmental remediation, that agencies are expected to release between 2026 and 2028. If you have any questions or need help with the Mystic bids, contact Lohfeld Consulting.

Description of Mystic Bids (Updated 11/03/2025)

1. Pharmaceutical Prime Vendor III (PPV III)
   Agency: Dept. of Veterans Affairs (VA), Veterans Health Administration (VHA)
   NAICS Code: 325412 – Pharmaceutical Preparation Manufacturing
   GovWin Opp ID: 230579
   RFP Type: Indefinite Delivery/Indefinite Quantity (IDIQ)
   Competition Type: Full and Open/Unrestricted
   Value: $61.8B
   RFP Date: 02/2028
   Description: The VA has an ongoing need for pharmaceutical distribution services to facilities across the U.S., its territories, and select international locations. Since moving away from its depot system in the early 1990s, the VA has relied on the Pharmaceutical Prime Vendor (PPV) program, which uses just-in-time inventory management, advanced ordering software, and prompt payment systems. This program supplies not only VA facilities but also other federal agencies, including the Indian Health Service and Bureau of Prisons, as well as eligible state veterans’ homes. Contractors must maintain a web-based ordering system, comply with Drug Enforcement Administration (DEA) requirements for controlled substances, provide next-day or 72-hour delivery depending on location, and deliver robust reporting, with pricing tied to federal contracts or, where needed, wholesale acquisition cost (WAC) generics.
   Status: On October 6, 2025, the government released a sources sought notice (SSN). It seeks qualified sources (especially Service-Disabled Veteran-Owned Small Businesses (SDVOSBs) and Veteran-Owned Small Businesses (VOSBs)) capable of providing nationwide and overseas pharmaceutical distribution services to the VA and other federal facilities. The PPV contractor must stock, manage, and distribute pharmaceuticals priced under federal contract vehicles; provide web-based ordering with DEA-compliant electronic controlled-substance orders; and ensure next-day CONUS delivery and 72-hour OCONUS delivery. Respondents must demonstrate capabilities in cold chain logistics, inventory forecasting, electronic data interchange (EDI), real-time pricing, and reporting compliance under the Drug Supply Chain Security Act (DSCSA). The SSN requests detailed information on company experience, distribution network, ordering systems, customer support, inventory management, and prior contract history to inform the VA’s acquisition strategy. Responses are due by 11:00 AM CST on November 3, 2025,and will help determine whether to set aside the procurement for veteran-owned businesses or pursue a broader competition. This notice is for planning purposes only and will not result in an immediate solicitation or contract award. The McKesson Corporation is the incumbent contractor.
2. Next Generation Network Infrastructure RFI on Telecommunications Information Technology (NGNI)
   Agency: General Services Administration (GSA), Federal Acquisition Service (FAS) Information Technology Category (ITC)
   NAICS Code: 517111 – Wired Telecommunications Carriers
   GovWin Opp ID: 240041
   RFP Type: Undetermined
   Competition Type: Undetermined
   Value: $50B
   RFP Date: 07/2027
   Description: GSA is developing its NGNI strategy to succeed the Enterprise Infrastructure Solutions (EIS) contracts, which expire in July 2032. Established in 2017, EIS provides federal agencies with a comprehensive suite of telecommunications and IT services, including data, voice, cloud, wireless, satellite, and managed network solutions, through multiple award IDIQ contracts. Agencies access these services by obtaining a Delegation of Procurement Authority (DPA) and issuing task orders in compliance with fair opportunity procedures. NGNI is designed to anticipate future market trends and ensure agencies continue to benefit from modern, secure, and cost-effective infrastructure solutions.
   Status: GSA held an Industry Day on May 31, 2024, which focused on the EIS program scope and planning for NGNI.
3. Superfund Remedial Acquisition Framework (RAF) (2.0)
   Agency: Environmental Protection Agency (EPA) Superfund
   NAICS Code: 562910 – Environmental Remediation Services
   GovWin Opp ID: 253722
   RFP Type: Undetermined
   Competition Type: Undetermined
   Value: $18.5B
   RFP Date: 02/2026
   Description: The EPA Superfund program has an ongoing need for architect/engineer, technical, and management services to address releases or threatened releases of hazardous substances that endanger human health and the environment. Under its Superfund Remedial Action Framework, the EPA provides site investigation, design, remediation, and long-term operational support, in accordance with laws such as the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), the Superfund Amendments and Reauthorization Act of 1986 (SARA), and the Stafford Disaster Relief and Emergency Assistance Act. The framework is organized into three primary suites of contracts: Design and Engineering Services (DES) for planning and design; Remediation Environmental Services (RES) for cleanup and construction; and Environmental Services and Operations (ESO) for remedy operations and technical support. These contracts will be awarded under national solicitations, competed at the task order level, and may also incorporate specialized munitions expertise when appropriate.
   Status: The EPA released a preliminary request for information (RFI) on November 15, 2024.
4. Cyber Dynamic Operational Multiple Award Environment (DOME)
   Agency: Dept. of Homeland Security (DHS), Cybersecurity and Infrastructure Security Agency (CISA)
   NAICS Code: 541512 – Computer Systems Design Services
   GovWin Opp ID: 252038
   RFP Type: IDIQ
   Competition Type: Undetermined
   Value: $18B
   RFP Date: 02/2026
   Description: CISA is planning to establish an IDIQ contract for cybersecurity products and services. This vehicle will help federal agencies strengthen cyber defenses by providing scalable solutions in project management, requirements management, capability implementation, operations and sustainment, and solution development, along with access to cybersecurity products and tools. The initiative aims to improve IT flexibility, reduce redundant infrastructure, and resolve procurement challenges such as shelfware, transferability issues, and inconsistent buying practices. By streamlining acquisition and aligning with CISA’s mission, the IDIQ will enable agencies to access modern, cost-effective, and responsive cybersecurity capabilities.
   Status: The bid appears in DHS’s July 2025 opportunities list (Fourth Wednesday Slide).
5. Test and Evaluation Technologies for Ranges, Armaments, and Spectrum (TETRAS) III
   Agency: Dept. of the Air Force, Air Force Materiel Command (AFMC), Air Force Test Center (AFTC)
   NAICS Code: 541715 – Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
   GovWin Opp ID: 251026
   RFP Type: IDIQ
   Competition Type: Undetermined
   Value: $20B
   RFP Date: 06/2027
   Description: AFMC’s 96th Test Wing has an ongoing need for airborne and range instrumentation, infrastructure, facilities, and technical expertise to support testing and fielding of advanced warfighting capabilities. The TETRAS III IDIQ contract will provide innovative test and evaluation solutions for weapons systems; command, control, communications, computers, cyber-defense, combat systems, intelligence, surveillance and reconnaissance (C6ISR); electronic combat systems; munitions; and emerging technologies, including hypersonics, directed energy, and cyber. It is designed to deliver rapid, flexible, and scalable support that enhances test missions, increases throughput, and adapts to evolving national defense requirements. By modernizing test ranges and capabilities, TETRAS III ensures the Department of Defense (DOD) can validate and transition cutting-edge systems with speed and agility.
   Status: The Air Force published the TETRAS III Industry Day Q&A responses on June 4, 2025.
6. Joint Warfighting Cloud Capability Next (JWCC Next)
   Agency: Dept. of Defense (DOD), Defense Information Systems Agency (DISA)
   NAICS Code: 518210 – Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services
   GovWin Opp ID: 249532
   RFP Type: IDIQ
   Competition Type: Full and Open/Unrestricted
   Value: $9B
   RFP Date: 03/2026
   Description: The program will deliver Anything as a Service (XaaS) across all classification levels, from strategic to tactical operations, including disconnected, disrupted, intermittent, and limited connectivity (DDIL) environments. JWCC Next seeks to use commercial cloud innovation, artificial intelligence (AI), and machine learning (ML) to modernize DOD software and hardware at scale. Key requirements include global availability, parity of services across security domains, integrated cross-domain solutions, enhanced cybersecurity, edge capabilities, and support for emerging technologies.
   Status: DOD listed JWCC Next in its Q4 FY25 Acquisition Opportunities Forecast.
7. Information Technology Support Services Contract (ITSSC)
   Agency: Social Security Administration (SSA)
   NAICS Code: 541519 – Other Computer Related Services
   GovWin Opp ID: 246544
   RFP Type: IDIQ
   Competition Type: Full and Open/Unrestricted
   Value: $7.8B
   RFP Date: 01/2026
   Description: As workloads rise, the SSA will rely on automation and advanced IT solutions to deliver efficient, cost-effective services for programs such as Social Security and Supplemental Security Income. Contractor support will cover the full systems development lifecycle, including software engineering, database administration, systems security, and lifecycle management of IT and telecommunications systems. These efforts are essential to ensuring productivity, responsiveness to legislative changes, and improved customer service for millions of Americans.
   Status: CGI Federal, Leidos, and Northrup Grumman hold the current contracts, which will expire on September 28, 2026.
8. G2S Open Season
   Agency: Dept. of Defense (DOD), Defense Logistics Agency (DLA)
   NAICS Code: 334419 – Other Electronic Component Manufacturing
   GovWin Opp ID: 257632
   RFP Type: IDIQ
   Competition Type: Undetermined
   Value: $5B
   RFP Date: 03/2026
   Description: DLA has an ongoing requirement for the Command, Control, Computers, Communications, Cyber, Intelligence, Surveillance and Reconnaissance (C5ISR) Gateway to Sustainment (G2S) program to support U.S. Army Communications and Electronics Command (CECOM) systems. This effort covers both commercial and non-commercial items and services, including standard and non-standard equipment, testing, repair, upgrades, engineering studies, and obsolescence monitoring. Support spans a wide range of mission areas, including tactical and strategic communications; cyberspace operations; electronic warfare; aircraft survivability; counter-improvised explosive devices (C-IED) operations; intelligence, surveillance, reconnaissance, and targeting (ISR&T); radar systems; and navigation. It also includes the sustainment of enabling systems, such as power generation, environmental controls, avionics, and air traffic control, to ensure operational readiness across the Army’s C5ISR enterprise.
   Status: On August 27, 2025, DLA published a market survey with responses due on September 30, 2025.
9. GEN VI Human Resources Solutions Support
   Agency: Dept. of the Army, Assistant Secretary of the Army for Acquisition, Logistics, and Technology (ASA(ALT)), Program Executive Office Enterprise Information Systems (PEO EIS), Human Resources (HR) Solutions Program Directorate
   NAICS Code: 541612 – Human Resources Consulting Services
   GovWin Opp ID: 233006
   RFP Type: IDIQ
   Competition Type: Undetermined
   Value: $7.6B
   RFP Date: 09/2026
   Description: The Army requires contractor support for Personnel Life Cycle Support Services (PLS) and Recruiting, Management, and Administrative Support (R-MAS). The PLS scope covers the full HR lifecycle—including personnel structure, distribution, training, deployment, compensation, sustainment, transition, and data administration, along with tasks such as policy analysis, process reengineering, risk management, and well-being programs. The R-MAS requirement supports recruiting and retention through program management, IT, policy development, data analysis, logistical/operational support, training, outreach, and general administration. Together, these services aim to ensure effective personnel management, recruiting, and retention across the Army’s workforce.
   Status: The GEN VI contracts are set to expire on September 3, 2028. The primary contractors are Magellan Healthcare, Inc., 360 Patriot Enterprises, Management Analysis Technologies, and Strategic Resources, Inc.
10. Military and Family Life Counseling Services (MFLC)
    Agency: Dept. of Defense (DOD), Office of the Secretary of Defense (OSD), Office of the Deputy Assistant Secretary of Defense for Military Community and Family Policy (MC&FP)
    NAICS Code: 624190 – Other Individual and Family Services
    GovWin Opp ID: 227544
    RFP Type: Other
    Competition Type: Full and Open/Unrestricted
    Value: $4B
    RFP Date: 06/2026
    Description: MFLC provides in-person, confidential, non-medical counseling services to military members, their spouses, caregivers, and children, both within the U.S. and overseas. Services include traditional counseling, walk-around sessions, and specialized support tailored to adults, children, youth, and military leaders. Contractor responsibilities encompass program management, transition support, counseling and outreach, on-demand and surge services, and optional geographic or virtual support capabilities.
    Status: The current contracts (Leidos and Magellan Healthcare, Inc.) expire on January 31, 2028.
11. OASIS+ Multi-Agency Contract (On-Ramp)
    Agency: General Services Administration (GSA), Federal Acquisition Service (FAS)
    NAICS Codes: 541990 – All Other Professional, Scientific and Technical Services; 238220 – Plumbing, Heating, and Air-Conditioning Contractors; 238290 – Other Building Equipment Contractors; etc. (see website for complete list)
    GovWin Opp ID: 201043
    RFP Type: IDIQ – MAC
    Competition Type: Full and Open/Unrestricted and Small Business Set-Asides
    Value: $133B (for OASIS+)
    RFP Date: Unknown
    Description: OASIS+ is a broad and flexible IDIQ designed to reduce contract duplication, lower acquisition costs, and provide agencies with easier access to highly qualified vendors offering integrated, commercial, and non-commercial services across multiple domains. Its purpose is to meet increasingly complex and evolving federal mission needs—including modernization, environmental services, intelligence, logistics, research and development (R&D), facilities support, and enterprise-level solutions—through a contract structure that allows continuous on-ramping of new vendors, multiple pricing and contract types, and enhanced competition at the task order level.
    Status: On August 26, 2025, GSA posted answers to 240+ questions. In the answers, GSA noted that it’s using its findings to decide on its future course of action for OASIS+. This could involve adding new domains (all or a subset), on-ramping new contractors to the original domains, or allowing existing contractors to add new domains via contract modification. On July 8, 2025, the GSA’s Office of Professional Services and Human Capital Categories closed the OASIS+ Phase II RFI for the new IDIQ best-in-class (BIC) multi-agency contract program. The RFI was posted on SAM.gov on June 17, 2025. GSA received more than 1,200 responses to the RFI seeking feedback from service providers within the industry to develop evaluation criteria (scoring cards) and refine technical capabilities for five new potential domains: Financial Services, Human Capital, Marketing and Public Relations, Social Services, and Business Administration.

Large Government Lab Contracts

There are multiple opportunities for managing large laboratory and R&D facilities. However, the opportunities are limited to a select number of bidders with specialized expertise. These opportunities include:

• Oak Ridge Institute Science and Education Contract (ORISE): RFP Date: 02/2026; GovWin ID: 228984; Agency: Dept. of Energy (DOE) Office of Science; Value: $3.2B.
• One Professional Services Solution (HOPSS): RFP Date: 05/2026; GovWin ID: 249137; Agency: Dept. of Health and Human Services (HHS), National Institutes of Health (NIH); Value: $3.6B.
• Management and Operation of Sandia National Laboratory (SNL): RFP Date: 06/2026; GovWin ID: 176048; Agency: Dept. of Energy (DOE); Value: $50B.
• Management and Operation of the Nevada National Security Site: RFP Date: 11/2026; GovWin ID: 223041; Agency: Dept. of Energy (DOE), National Nuclear Safety Administration (NNSA), Nevada Operations Offices (DOE/NV); Value: $13B.
• Management and Operation of the Princeton Physics Laboratory (PPPL M&O): RFP Date: 12/2026; GovWin ID: 60483; Agency: Dept. of Energy (DOE); Value: $14.6B.
• Los Alamos National Laboratory Management and Operations (LANL M&O): RFP Date: 04/2027; GovWin ID: 235406; Agency: Dept. of Energy (DOE), National Nuclear Security Administration (NNSA); Value: $32B.

Big Construction and Installation Contracts

There are also several significant construction projects sponsored by the U.S. Army Corps of Engineers (USACE) and Department of Health and Human Services (HHS):

• Programmatic Acquisition for Regional Construction Requirements MATOCS: RFP Date: 07/2026; GovWin ID: 254411; Agency: USACE Sacramento District; Value: $5B.
• Electronic Security Systems 8^th Generation (ESS VIII): RFP Date: 09/2026; GovWin ID: 255358; Agency: USACE, U.S. Army Engineering and Support Center Huntsville (CEHNC); Value: $2.5B.
• Multiple Award Construction Contract (NIH FY2025 MACC): RFP Date: 03/2027; GovWin ID: 250357; Agency: HHS, National Institutes of Health (NIH); Value: $3B.

Care Facilities and Public Health Contracts

There are several large contracts focused on providing shelter or public health services that may not come to fruition based on the current administration’s focus:

• Full Service Influx Care Facility Services: RFP Date: 01/2027; GovWin ID: 248823; Agency: Dept. of Health and Human Services (HHS), Administration for Children and Families; Value: $75B
• Medical Countermeasures (MCMs) for Pandemic Influenza and Emerging Diseases Preparedness and Response: RFP Date: 02/2026; GovWin ID: 235025; Agency: HHS; Value: $23.8B.
• Vaccines for Children: RFP Date: 12/2025; GovWin ID: 254344; Agency: Dept. of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC); Value: $9.4B.

Further Updates

• Last February, federal contractors were eagerly anticipating the release of the Army’s Marketplace for the Acquisition of Professional Services (MAPS) RFP. Then, on March 26, 2025, the Army released a modification indicating the bid was going into a reflective delay. On September 4, 2025, the Army stated that it is awaiting instructions on how to proceed.
• The Chief Information Officer Commodities Store (CIO-CS) is in the process of transferring to the General Services Administration. The incumbent contracts expired on October 30, 2025. We will have to stay tuned for details.

Conclusion

Positioning early for high-profile Mystic bids is the key to success. At Lohfeld Consulting, we specialize in helping contractors capture and develop proposals for these game-changing opportunities. From pipeline strategy and capture planning to proposal management, writing, and reviews, our experts ensure you are ready to compete and win. If your team is targeting one or more of these Mystic Bids, contact us today to gain the strategic edge that makes the difference.

Relevant Information

• Use Mega Bids to Drive Business Growth in October 2025

• Use Mighty Bids to Drive Mid/Small Company Growth Now

• Use Mini Bids to Drive Small Business Growth Now

By Brenda Crist, Vice President at Lohfeld Consulting Group, MPA, CPP APMP Fellow

Lohfeld Consulting Group has proven results specializing in helping companies create winning captures and proposals. As the premier capture and proposal services consulting firm focused exclusively on government markets, we provide expert assistance to government contractors in Capture Planning and Strategy, Proposal Management and Writing, Capture and Proposal Process and Infrastructure, and Training. In the last 3 years, we’ve supported over 550 proposals winning more than $170B for our clients—including the Top 10 government contractors. Lohfeld Consulting Group is your “go-to” capture and proposal source! Start winning by contacting us at www.lohfeldconsulting.com and join us on LinkedIn, Facebook, and YouTube^(TM).